Oncology

Makes a portable cryoablation device that lets nurses and community health workers treat precancerous cervical cells at the point of care in primary care clinics.

Cleveland Diagnostics develops blood tests that read structural changes in cancer-related proteins. Its IsoPSA test helps urologists decide whether to biopsy men with elevated PSA.

Cordance Medical is developing a focused ultrasound system that temporarily opens the blood-brain barrier for drug delivery and liquid biopsy in brain tumors.

Develops blood-based cancer screening tests built on cell-free DNA methylation and machine learning. SimpleScreen CRC is its first FDA-approved product; listed on Nasdaq as FRNM in July 2026.

Galvanize Therapeutics builds pulsed electric field ablation systems. Aliya is cleared for soft tissue ablation and is being studied in solid tumors; RheOx targets chronic bronchitis.

Sells GammaTile, a bioresorbable brachytherapy implant placed in the resection cavity during brain tumor surgery. Cleared under 510(k) with product code KXK and used at more than 150 US cancer centers.

HistoSonics makes the Edison histotripsy system, which uses focused ultrasound to destroy liver tumors without incisions, heat or radiation.

Developing a genetically encoded biomaterial that plastic and reconstructive surgeons use to regenerate fat tissue. Spun out of work by Duke professor Ashutosh Chilkoti.

Builds devices that let patients manage parts of cancer treatment at home, including a wearable aimed at preventing chemotherapy hair loss.

Handheld imaging device using frequency domain near infrared spectroscopy to indicate within a week of starting treatment whether a breast cancer therapy is working.

Builds optical coherence tomography systems with AI detection for assessing surgical margins during cancer surgery. Listed on the TSX Venture Exchange as PINK.