Respiratory & Sleep

Makes AcuPebble, a wearable acoustic sensor worn on the neck that records breathing and heart sounds at home to diagnose sleep apnea.

Singapore company behind AeviceMD, a wearable stethoscope for remote respiratory monitoring, plus a cleared software module that flags suspected wheeze in recorded lung sounds.

Builds the BREATHE Airway Scaffold, an implant that relieves pressure in overinflated lungs in severe emphysema without removing healthy tissue. Built at The Foundry and still investigational.

Makes EOlife, a real-time ventilation feedback device that measures the air volume delivered to a cardiac arrest patient's lungs and shows rescuers when to adjust.

Developing an automated cuff-pressure controller for endotracheal and tracheostomy tubes.

Galvanize Therapeutics builds pulsed electric field ablation systems. Aliya is cleared for soft tissue ablation and is being studied in solid tumors; RheOx targets chronic bronchitis.

The Happy Ring is a sensor ring cleared to diagnose obstructive sleep apnea at home. The company is building a home care platform around it.

Makes a wireless patch for continuous breathing monitoring, first aimed at patient safety during procedural sedation.

Builds airway and GI stents, cryo biopsy probes and steerable endobronchial instruments, plus molecular diagnostics for lung cancer triage. Formed under Ajax Health in 2023 and acquired Thoracent in 2025.

Israeli software startup whose CPETWise platform automates analysis, interpretation and reporting of cardiopulmonary exercise tests. FDA cleared CPETWise under K260242 on August 20, 2026, 206 days after receiving the traditional 510(k).

Neurent Medical makes NEUROMARK, a radiofrequency system that ablates the posterior nasal nerves to treat chronic rhinitis.

Makes the Prana System, a single-use image-guided electrosurgical tool that combines CT-guided targeting with tissue excision. It was cleared in April 2026 to remove tissue and control bleeding.

Makes PulmVac, a wearable chest drainage device for pneumothorax with real-time pressure monitoring.

Builds Sylvee, a wearable chest sensor that uses acoustic resonance to measure trapped air and lung volumes at home for people with COPD. Won MedTech Innovator in 2024.

Makes the Kricket positive airway pressure device, which runs its KPAP algorithm to deliver pressure only during parts of the breath cycle rather than holding one fixed pressure.

Spiro Medical is developing an implantable spinal nerve stimulator to reduce symptoms in severe, uncontrolled asthma.

Builds the Bonhawa high flow oxygen therapy system for patients with respiratory insufficiency. FDA cleared the system in October 2023.

Builds organ preservation and ex vivo lung perfusion systems for transplant, spun out of Toronto General Hospital in 2021.

Runs the Spire remote patient monitoring system with wearable Health Tags for continuous cardiopulmonary tracking, aimed at catching COPD deterioration before symptoms appear.